Dabi, with his deadly blue flames and tragic past, stands out as a formidable villain in My Hero Academia. His quest for vengeance against hero society exposes deep scars, challenging the ideals heroes uphold and adding layers of complexity to his role as a compelling antagonist.

Sukuna, the King of Curses, embodies pure malevolence in Jujutsu Kaisen. Sharing a body with protagonist Yuji Itadori, Sukuna's unpredictable nature and overwhelming power create a constant tension. His presence looms large, influencing every decision and battle in the series.

Eren Yeager's transformation from hero to villain is one of the most significant twists in Attack on Titan. Driven by a warped sense of freedom, Eren's destructive path challenges the very notion of good and evil, making him one of the most complex antagonists in anime history.

Rachel's betrayal in Tower of God makes her one of anime's most despised villains. Her selfish ambition and willingness to betray her closest friend, Bam, stem from deep insecurities. This complex mix of vulnerability and ruthlessness adds a tragic depth to her character.

Kaidou, the unyielding force behind the Beasts Pirates, is a towering menace in One Piece. Known as the Strongest Creature in the World, Kaidou’s desire for chaos and destruction poses a monumental challenge to Luffy and his crew, cementing his place as an iconic anime villain.

Enrico Pucci’s fanatical pursuit of heaven in JoJo's Bizarre Adventure leads to devastating consequences. His religious zealotry, combined with his powerful Stand abilities, makes him a formidable and terrifying villain, whose impact on the series is both profound and lasting.

Nakahara Chuuya, with his gravity-defying abilities, is a formidable opponent in Bungou Stray Dogs. His complex relationship with Dazai adds layers to his character, making him more than just an antagonist—a tragic figure caught in a world of power and betrayal.

Askeladd, the cunning Viking leader in Vinland Saga, is a master strategist and ruthless warrior. His complex motivations and deep-rooted ideals drive the story forward, making him one of anime's most multifaceted villains, whose actions resonate throughout the series.

Makima, the manipulative and enigmatic villain in Chainsaw Man, is a master of psychological manipulation. Her cold, calculated approach to achieving her goals and her hidden agenda make her one of the most chilling and unpredictable villains in the modern anime landscape.

Isabella from The Promised Neverland is a chilling figure, hiding a calculating mind behind her nurturing facade. As the caretaker of Grace Field House, she betrays the very children she raises, making her a complex and unforgettable antagonist in modern anime.